Authors:
Ulrich Spiegl, M.D., Scott Faucett, M.D., Marilee Horan, M.P.H., Peter Millett, M.D., M.Sc.
Abstract:
Introduction
There is little information to guide clinicians about the best treatment for young patients with glenohumeral osteoarthritis (OA). The purpose of this study was to perform a decision analysis comparing arthroscopic management with total shoulder arthroplasty (TSA) for the surgical treatment of glenohumeral OA and to determine the effect of age at surgery on the long-term outcome of each strategy.
Methods
A Markov decision model was constructed to compare arthroscopic management and TSA in patients with glenohumeral OA. The rates of surgical complications, revision surgery, and death were derived from the literature for each treatment. Additionally, the outcomes, complication rates, revision surgery rates, and the survivorship after arthroscopic management and TSA were included. Outcomes were measured as quality-adjusted life years (QALYs) and the principal outcome measure was the mean QALYs for each strategy. The model was tested over a range of ages to determine the sensitivity of the outcome based on the age at the initial procedure.
Results
The model demonstrated that arthroscopic management was the preferred treatment strategy for patients under 47 and that TSA was the preferred treatment strategy for those over 65 years old. The model was sensitive to a number of factors which included: (1) age at the initial surgery, (2) utilities of the well states after TSA and arthroscopic management, (3) survivorship of TSA and arthroscopic management, and (4) the probability of failure for arthroscopic management and TSA. For the analysis in this young and active population, the utility after arthroscopic management was assumed to be 0.82, while the utility after TSA was set at 0.85. The model was quite sensitive to changes in the utility, and a reduction in the utility of only 0.01 after arthroscopic management decreased the threshold age favoring arthroscopic management from 65 to 47 years.
Conclusion
Arthroscopic management for OA is the preferred initial strategy for younger patients that have failed conservative treatment, while TSA is preferred in older patients. The decision analysis was most sensitive to patient age and the utility after arthroscopic management and TSA. TSA was clearly favored in patients over 65 while arthroscopic management was preferred in those less than 47. Based on the high sensitivity of the model, the data supports two reasonable treatment strategies in patients between 47 and 65 years, where both treatment options are reasonable. Clearly, further mid- and long-term studies evaluating glenohumeral joint preserving arthroscopic strategies and TSA in young patients are warranted to help clinicians with surgical decision-making.
For the complete study: Glenohumeral Osteoarthritis in Young Patients: When is Arthroscopic Management Indicated? A Markov Decision Analysis